E2B v1.63 Beta 2 available with auto-suggest feature!
This will suggest a better, alternative file extension if it thinks that .ISO may not work correctly. You can accept the suggested alternative and it will run the .ISO file as if it had the suggested alternative file extension (or run it as .ISO).
Also I have added latest grub4dos 0.4.6a which has a bugfix for NTFS (some files would not boot at all, but would boot under 0.4.5c).
See blogspot page for more details.